Keratin 2 (KRT2) Peptid
KRT2
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
Produktnummer ABIN979130
Kurzübersicht für Keratin 2 (KRT2) Peptid (ABIN979130)
Target
Keratin 2 (KRT2)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-KRT2A antibody (Catalog #: ARP41735_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Keratin 2 (KRT2)
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Hintergrund
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KRT2A is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Alias Symbols: KRT2E, KRTE, K2e, CK-2e, KRT2A
Protein Interaction Partner: EVPL,SMAD3
Protein Size: 639 -
Molekulargewicht
- 70 kDa
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Gen-ID
- 3849
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NCBI Accession
- NM_000423, NP_000414
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UniProt
- P35908
Target
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